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An Ancient Ant-Bacteria Partnership to Protect Fungus (NYT-2018)

7 July 2019

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New York Times title: An Ancient Ant-Bacteria Partnership to Protect Fungus

NYT subtitle: Amber specimens indicate that fungus-farming ants have been cooperating with antimicrobial bacteria for tens of millions of years.

Publication date: 6 October 2018

“The dawn of agriculture did not rise with Neolithic humans in Mesopotamia. Or in China. Or in the Levant. No, it bloomed in the rain forests of South America some 60 million years ago. And the first farmers were humble ants.

Long before early humans cultivated wheat, barley, lentils and flax, ancient leafcutter ants raised fungus. And like human farmers, the ants had to fend off crop pests, particularly a parasitic fungal disease.

“If the fungus dies, the ants die,” said Cameron Currie, a microbial ecologist at the University of Wisconsin-Madison who studies the fungal-farming ants and their mutually beneficial relationships with other species.

To fight the pestilence, the ants aligned themselves with a bacteria that produces a chemical capable of subduing the parasite. Now, Dr. Currie and his colleagues have found evidence that suggests that the partnership between ants and antimicrobial bacteria has existed for tens of millions of years. The key clues came from two 20-million-year-old ants that were discovered, trapped in amber, in the Dominican Republic.

One of the fossilized ants had specialized pockets on its head, called crypts, that are also seen on modern ants. The crypts are known to house the fungus-protecting bacteria, called actinobacteria. The other ant specimen was entombed with gas bubbles on its body, likely produced by the respiration of the actinobacteria.

“It’s kind of like the ants are walking pharmaceutical factories,” said Dr. Currie, who is an author of the study, which appeared Monday in the journal Proceedings of the National Academy of Sciences. “This indicates that, like in the way ants predated us in growing crops, they also predated us by tens of millions of years in associating with microbes to produce antibiotics.”

Hongjie Li, an evolutionary biologist in Dr. Currie’s lab and the lead author of the study, was inspecting the amber specimens last summer, using a scanning electron microscope at the Smithsonian Institution, when he and his colleagues found signs that the amber ants carried bacteria in a manner similar to modern ants.

“It was a shock to me,” said Dr. Li.

The team combined that finding and published data on 69 other ant species to reconstruct the ant’s evolutionary tree. The resultsindicated that the ants established their partnership with the bacteria tens of millions of years ago, shortly after they developed their fungus-farming abilities.

The partnership has been a vital part of the ant’s evolutionary story, and it continues to reveal itself.

It is seen in modern leaf-cutting ants, which take such tender care of the fungus that when a new queen is ready to start her own nest, she will cut off a piece of it from her parent’s fungus garden and carry it in her mouth until she finds a spot to begin her colony. Some garden-tending ants cover their entire bodies with a white coat of the bacteria in order to protect the fungus.

“These ants have been associated with this antimicrobial-producing bacteria arguably since 40 to 55 million years ago,” said Dr. Currie. “Which is fascinating, because humans have been using antibiotics for about 60 to 70 years.” ”

Sources:

https://www.nytimes.com/2018/10/06/science/ants-fungus-amber.html

https://www.nytimes.com/2017/04/11/science/ant-fungus-farmers-evolution.html

https://www.bnr.nl/radio/wetenschap-vandaag/10308361/mieren-met-een-moestuin

https://www.nature.com/articles/ncomms12233

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